Aminoacyl tRNA Synthetases: Exemplars of the Fluidity of Protein Structure and Function through Phylogenetic History

Earlier this year I was afforded the opportunity to hear Paul Schimmel, of the Scripps Research Institute, lecture on aminoacyl transfer RNA (tRNA) synthetases (aaRSs), a topic on which he is a leading authority.  These enzymes attach particular amino acids to specific tRNA molecules for incorporating those amino acids into growing polypeptide chains by ribosomes.  […]

from The Evolution and Medicine Review http://ift.tt/1Y52L1y