Overcoming cancer evolution with collateral sensitivity and drug holidays

It is now widely understood that cancers evade treatment by evolving drug resistance – in much the same way as microbes acquire resistance to antibiotics. This is why patients can relapse even after courses of modern targeted cancer therapies. Encountering this with drug cocktails sometimes fails because the evolution of resistance to one drug sometimes results in […]

from The Evolution and Medicine Review http://ift.tt/2p0GXHe